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Receptor

Search Result - 1

HMRbase accession number	20018
Swiss-prot Accession number	Q05192 (Sequence in FASTA format)
Description	Nuclear hormone receptor FTZ-F1 beta (dHR39).
Source organism	Drosophila melanogaster (Fruit fly)
Taxonomical Classification	Eukaryota; Metazoa; Arthropoda; Hexapoda; Insecta; Pterygota;Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha;Ephydroidea; Drosophilidae; Drosophila.
Subcellular location	Nucleus
Developmental Stage	Expressed at all stages.
Similarity	Belongs to the nuclear hormone receptor family. NR5 subfamily. Contains 1 nuclear receptor DNA-binding domain.
Tissue Specificity	Expressed throughout the blastodermal layer in early embryos. At later stages, strong expression is observed in the brain, ventral cord and hindgut.
Post translational modification	N/A
Function	Acts as a cofactor to fushi tarazu (ftz). Facilitates the binding of ftz to DNA. Binds the sequence element 5'- YCYYGGYCR-3' in the zebra element of ftz. Probably also functions as a receptor for a yet unknown ligand.
Protein Length	808 Amino acids
Molecular weight	87314
Domain Name	Hormone_recep  zf-C4
References	1  PubMed abstract 8382937 2  PubMed abstract 8479913 3  PubMed abstract 10731132 4  PubMed abstract 12537572 5  PubMed abstract 12537569 6  PubMed abstract 8164672
Hormone	N/A
Gene ID	35398
PDB ID	N/A
Drugpedia	wiki
Comments	!Hormone for this Receptor are either unknown or have not yet been curated

Search Result - 2

HMRbase accession number	20046
Swiss-prot Accession number	P33244 (Sequence in FASTA format)
Description	Nuclear hormone receptor FTZ-F1 (FTZ-F1 alpha).
Source organism	Drosophila melanogaster (Fruit fly)
Taxonomical Classification	Eukaryota; Metazoa; Arthropoda; Hexapoda; Insecta; Pterygota;Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha;Ephydroidea; Drosophilidae; Drosophila.
Subcellular location	Nucleus
Developmental Stage	First appears in blastoderm embryos. It is absent in subsequent embryo stages, and then reappears in late embryogenesis to be found in larvae, pupae and adults.
Similarity	Belongs to the nuclear hormone receptor family. NR5 subfamily. Contains 1 nuclear receptor DNA-binding domain.
Tissue Specificity	Expression in the parasegmental primordia of the embryonic blastoderm.
Post translational modification	N/A
Function	Acts as a cofactor to fushi tarazu (ftz). Facilitates the binding of ftz to DNA. Binds the sequence element 5'- YCYYGGYCR-3' in the zebra element of ftz. Probably also functions as a receptor for a yet unknown ligand.
Protein Length	1027 Amino acids
Molecular weight	108418
Domain Name	zf-C4  Hormone_recep
References	1  PubMed abstract 1709303 2  PubMed abstract 8096644 3  PubMed abstract 10731132 4  PubMed abstract 12537572 5  PubMed abstract 12537569 6  PubMed abstract 8164672 7  PubMed abstract 1448096 8  PubMed abstract 9020363 9  PubMed abstract 9020364
Hormone	N/A
Gene ID	40045
PDB ID	2IZ2
Drugpedia	wiki
Comments	!Hormone for this Receptor are either unknown or have not yet been curated

Search Result - 3

HMRbase accession number	20057
Swiss-prot Accession number	P49869 (Sequence in FASTA format)
Description	Probable nuclear hormone receptor HR38 (dHR38).
Source organism	Drosophila melanogaster (Fruit fly)
Taxonomical Classification	Eukaryota; Metazoa; Arthropoda; Hexapoda; Insecta; Pterygota;Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha;Ephydroidea; Drosophilidae; Drosophila.
Subcellular location	Nucleus
Developmental Stage	Low levels in 0-8 hours embryos and adults. Higher in late embryogenesis and during larval and pupal stages. Short isoform is enriched in pupae and adults, long isoform in larvae.
Similarity	Belongs to the nuclear hormone receptor family. NR4 subfamily. Contains 1 nuclear receptor DNA-binding domain.
Tissue Specificity	Ubiquitously expressed in preblastoderm embryos, specifically in central nervous system and intestinal tract. Highly expressed in third instar larval imaginal disks and brain complexes, but not in ovaries.
Post translational modification	N/A
Function	Binds to NGFI-B response elements. Plays an important role in late stages of epidermal metamorphosis.
Protein Length	1073 Amino acids
Molecular weight	116992
Domain Name	zf-C4  Hormone_recep
References	1  PubMed abstract 7644522 2  PubMed abstract 9704500 3  PubMed abstract 9649534 4  PubMed abstract 10731132 5  PubMed abstract 12537572 6  PubMed abstract 7479849
Hormone	N/A
Gene ID	35332
PDB ID	1PDU
Drugpedia	wiki
Comments	!Hormone for this Receptor are either unknown or have not yet been curated

Search Result - 4

HMRbase accession number	20058
Swiss-prot Accession number	P31396 (Sequence in FASTA format)
Description	Probable nuclear hormone receptor HR3 (dHR3).
Source organism	Drosophila melanogaster (Fruit fly)
Taxonomical Classification	Eukaryota; Metazoa; Arthropoda; Hexapoda; Insecta; Pterygota;Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha;Ephydroidea; Drosophilidae; Drosophila.
Subcellular location	Nucleus (Potential)
Developmental Stage	N/A
Similarity	Belongs to the nuclear hormone receptor family. NR1 subfamily. Contains 1 nuclear receptor DNA-binding domain.
Tissue Specificity	N/A
Post translational modification	N/A
Function	Putative receptor whose ligand is not yet known.
Protein Length	487 Amino acids
Molecular weight	55285
Domain Name	zf-C4  Hormone_recep
References	1  PubMed abstract 1631105 2  PubMed abstract 10731132 3  PubMed abstract 12537572
Hormone	N/A
Gene ID	36073
PDB ID	N/A
Drugpedia	wiki
Comments	!Hormone for this Receptor are either unknown or have not yet been curated

Search Result - 5

HMRbase accession number	20061
Swiss-prot Accession number	Q9W539 (Sequence in FASTA format)
Description	Hormone receptor 4 (dHR4).
Source organism	Drosophila melanogaster (Fruit fly)
Taxonomical Classification	Eukaryota; Metazoa; Arthropoda; Hexapoda; Insecta; Pterygota;Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha;Ephydroidea; Drosophilidae; Drosophila.
Subcellular location	Nucleus
Developmental Stage	N/A
Similarity	Belongs to the nuclear hormone receptor family. NR1 subfamily. Contains 1 nuclear receptor DNA-binding domain.
Tissue Specificity	During L2 and L3 stages, strong constitutive expression is seen in the ring gland. Lower expression is detected in specific neurons of the central nervous system (CNS) (at protein level).
Post translational modification	N/A
Function	Coordinates growth and maturation by mediating endocrine responses to the attainment of critical weight during larval development. Plays a central role in the genetic cascades triggered by the steroid hormone ecdysone at the onset of metamorphosis, acting as both a repressor of the early ecdysone- induced regulatory genes and an inducer of the ftz-f1 midprepupal competence factor.
Protein Length	1518 Amino acids
Molecular weight	162655
Domain Name	zf-C4  Hormone_recep
References	1  PubMed abstract 15935763 2  PubMed abstract 10731132 3  PubMed abstract 12537572 4  PubMed abstract 10731137
Hormone	N/A
Gene ID	31162
PDB ID	N/A
Drugpedia	wiki
Comments	!Hormone for this Receptor are either unknown or have not yet been curated

Search Result - 6

HMRbase accession number	20062
Swiss-prot Accession number	Q24142 (Sequence in FASTA format)
Description	Nuclear hormone receptor HR78 (dHR78) (Nuclear receptor XR78E/F).
Source organism	Drosophila melanogaster (Fruit fly)
Taxonomical Classification	Eukaryota; Metazoa; Arthropoda; Hexapoda; Insecta; Pterygota;Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha;Ephydroidea; Drosophilidae; Drosophila.
Subcellular location	Nucleus
Developmental Stage	Highest expression in third instar larvae and prepupae.
Similarity	Belongs to the nuclear hormone receptor family. NR2 subfamily. Contains 1 nuclear receptor DNA-binding domain.
Tissue Specificity	N/A
Post translational modification	N/A
Function	Binds to direct repeats of the sequence 5'-AGGTCA-3'. Inhibits the ecdysone response. Plays an essential role in regulating molting of the tracheal cuticle during larval development.
Protein Length	601 Amino acids
Molecular weight	65393
Domain Name	zf-C4  Hormone_recep
References	1  PubMed abstract 7479849 2  PubMed abstract 7479823 3  PubMed abstract 10731132 4  PubMed abstract 12537572 5  PubMed abstract 12537569 6  PubMed abstract 14599492
Hormone	N/A
Gene ID	40378
PDB ID	N/A
Drugpedia	wiki
Comments	!Hormone for this Receptor are either unknown or have not yet been curated

Search Result - 7

HMRbase accession number	20063
Swiss-prot Accession number	Q24143 (Sequence in FASTA format)
Description	Nuclear hormone receptor HR96 (dHR96).
Source organism	Drosophila melanogaster (Fruit fly)
Taxonomical Classification	Eukaryota; Metazoa; Arthropoda; Hexapoda; Insecta; Pterygota;Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha;Ephydroidea; Drosophilidae; Drosophila.
Subcellular location	Nucleus
Developmental Stage	Highest expression in third-instar larvae and prepupae.
Similarity	Belongs to the nuclear hormone receptor family. NR1 subfamily. Contains 1 nuclear receptor DNA-binding domain.
Tissue Specificity	N/A
Post translational modification	N/A
Function	Binds selectively to the HSP27 20E response element.
Protein Length	723 Amino acids
Molecular weight	81029
Domain Name	zf-C4  Hormone_recep
References	1  PubMed abstract 7479849 2  PubMed abstract 10731132 3  PubMed abstract 12537572 4  PubMed abstract 12537569
Hormone	N/A
Gene ID	42993
PDB ID	N/A
Drugpedia	wiki
Comments	!Hormone for this Receptor are either unknown or have not yet been curated

Search Result - 8

HMRbase accession number	20322
Swiss-prot Accession number	P20905 (Sequence in FASTA format)
Description	5-hydroxytryptamine receptor 1 (5-HT receptor) (Serotonin receptor 1)(5HT-dro).
Source organism	Drosophila melanogaster (Fruit fly)
Taxonomical Classification	Eukaryota; Metazoa; Arthropoda; Hexapoda; Insecta; Pterygota;Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha;Ephydroidea; Drosophilidae; Drosophila.
Subcellular location	Cell membrane; multi-pass membrane protein
Developmental Stage	N/A
Similarity	Belongs to the G-protein coupled receptor 1 family.
Tissue Specificity	Expressed predominantly in adult heads.
Post translational modification	N/A
Function	This is one of the several different receptors for 5- hydroxytryptamine (serotonin), a biogenic hormone that functions as a neurotransmitter, a hormone, and a mitogen. The activity of this receptor is mediated by G proteins which activate adenylate cyclase.
Protein Length	564 Amino acids
Molecular weight	60861
Domain Name	7tm_1
References	1  PubMed abstract 2174167 2  PubMed abstract 10731132 3  PubMed abstract 12537572 4   Stapleton M., Brokstein P., Hong L., Agbayani A., Carlson J.W.,Champe M., Chavez C., Dorsett V., Dresnek D., Farfan D., Frise E.,George R.A., Gonzalez M., Guarin H., Kronmiller B., Li P.W., Liao G.,Miranda A., Mungall C.J., Nunoo J., Pacleb J.M., Paragas V., Park S.,Patel S., Phouanenavong S., Wan K.H., Yu C., Lewis S.E., Rubin G.M.,Celniker S.E.; Submitted (JUN-2002) to the EMBL/GenBank/DDBJ databases.
Hormone	N/A
Gene ID	43669
PDB ID	N/A
Drugpedia	wiki
Comments	!Hormone for this Receptor are either unknown or have not yet been curated

Search Result - 9

HMRbase accession number	20326
Swiss-prot Accession number	P28285 (Sequence in FASTA format)
Description	5-hydroxytryptamine receptor 2A (5-HT receptor) (Serotonin receptor2A).
Source organism	Drosophila melanogaster (Fruit fly)
Taxonomical Classification	Eukaryota; Metazoa; Arthropoda; Hexapoda; Insecta; Pterygota;Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha;Ephydroidea; Drosophilidae; Drosophila.
Subcellular location	Cell membrane; multi-pass membrane protein
Developmental Stage	N/A
Similarity	Belongs to the G-protein coupled receptor 1 family.
Tissue Specificity	N/A
Post translational modification	N/A
Function	This is one of the several different receptors for 5- hydroxytryptamine (serotonin), a biogenic hormone that functions as a neurotransmitter, a hormone, and a mitogen. The activity of this receptor is mediated by G proteins which inhibit adenylate cyclase.
Protein Length	834 Amino acids
Molecular weight	89521
Domain Name	7tm_1
References	1  PubMed abstract 1310937 2  PubMed abstract 10731132 3  PubMed abstract 12537572 4   Stapleton M., Carlson J.W., Chavez C., Frise E., George R.A.,Pacleb J.M., Park S., Wan K.H., Yu C., Celniker S.E.; Submitted (JUN-2005) to the EMBL/GenBank/DDBJ databases. 5  PubMed abstract 15611167 6  PubMed abstract 1310937 7  PubMed abstract 10731132 8  PubMed abstract 12537572 9   Stapleton M., Carlson J.W., Chavez C., Frise E., George R.A.,Pacleb J.M., Park S., Wan K.H., Yu C., Celniker S.E.; Submitted (JUN-2005) to the EMBL/GenBank/DDBJ databases. 10  PubMed abstract 15611167
Hormone	N/A
Gene ID	37196
PDB ID	N/A
Drugpedia	wiki
Comments	!Hormone for this Receptor are either unknown or have not yet been curated

Search Result - 10

HMRbase accession number	20333
Swiss-prot Accession number	P28286 (Sequence in FASTA format)
Description	5-hydroxytryptamine receptor 2B (5-HT receptor) (Serotonin receptor2B).
Source organism	Drosophila melanogaster (Fruit fly)
Taxonomical Classification	Eukaryota; Metazoa; Arthropoda; Hexapoda; Insecta; Pterygota;Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha;Ephydroidea; Drosophilidae; Drosophila.
Subcellular location	Cell membrane; multi-pass membrane protein
Developmental Stage	N/A
Similarity	Belongs to the G-protein coupled receptor 1 family.
Tissue Specificity	N/A
Post translational modification	N/A
Function	This is one of the several different receptors for 5- hydroxytryptamine (serotonin), a biogenic hormone that functions as a neurotransmitter, a hormone, and a mitogen. The activity of this receptor is mediated by G proteins which inhibit adenylate cyclase.
Protein Length	617 Amino acids
Molecular weight	67530
Domain Name	7tm_1
References	1  PubMed abstract 1310937 2  PubMed abstract 10731132 3  PubMed abstract 12537572
Hormone	N/A
Gene ID	37191
PDB ID	N/A
Drugpedia	wiki
Comments	!Hormone for this Receptor are either unknown or have not yet been curated

Search Result - 11

HMRbase accession number	20371
Swiss-prot Accession number	Q24511 (Sequence in FASTA format)
Description	Serotonin receptor 5-HT2 subtype.
Source organism	Drosophila melanogaster (Fruit fly)
Taxonomical Classification	Eukaryota; Metazoa; Arthropoda; Hexapoda; Insecta; Pterygota;Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha;Ephydroidea; Drosophilidae; Drosophila.
Subcellular location	Membrane; multi-pass membrane protein (By similarity).
Developmental Stage	N/A
Similarity	N/A
Tissue Specificity	N/A
Post translational modification	N/A
Function	N/A
Protein Length	868 Amino acids
Molecular weight	94957
Domain Name	7tm_1
References	1  PubMed abstract 7777527
Hormone	N/A
Gene ID	N/A
PDB ID	N/A
Drugpedia	wiki
Comments	!Hormone for this Receptor are either unknown or have not yet been curated

Search Result - 12

HMRbase accession number	20422
Swiss-prot Accession number	Q9VN38 (Sequence in FASTA format)
Description	CG1056-PA, isoform A.
Source organism	Drosophila melanogaster (Fruit fly)
Taxonomical Classification	Eukaryota; Metazoa; Arthropoda; Hexapoda; Insecta; Pterygota;Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha;Ephydroidea; Drosophilidae; Drosophila.
Subcellular location	Membrane; multi-pass membrane protein (By similarity).
Developmental Stage	N/A
Similarity	N/A
Tissue Specificity	N/A
Post translational modification	N/A
Function	N/A
Protein Length	868 Amino acids
Molecular weight	95065
Domain Name	N/A
References	1  PubMed abstract 10731132 2  PubMed abstract 16110336 3  PubMed abstract 12537568 4  PubMed abstract 12537572 5  PubMed abstract 12537573 6  PubMed abstract 12537574 7   Celniker S., Carlson J., Wan K., Pfeiffer B., Frise E., George R.,Hoskins R., Stapleton M., Pacleb J., Park S., Svirskas R., Smith E.,Yu C., Rubin G.; "Drosophila melanogaster release 4 sequence."; Submitted (AUG-2006) to the EMBL/GenBank/DDBJ databases. 8   Celniker S., Carlson J., Wan K., Frise E., Hoskins R., Park S.,Svirskas R., Rubin G.; Submitted (AUG-2006) to the EMBL/GenBank/DDBJ databases. 9   FlyBase; Submitted (AUG-2006) to the EMBL/GenBank/DDBJ databases. 10   Celniker S., Carlson J., Kennedy C., Wan K., Frise E., Hoskins R.,Park S., Svirskas R., Karpen G.; Submitted (AUG-2006) to the EMBL/GenBank/DDBJ databases.
Hormone	N/A
Gene ID	40575
PDB ID	N/A
Drugpedia	wiki
Comments	!Hormone for this Receptor are either unknown or have not yet been curated

Search Result - 13

HMRbase accession number	20606
Swiss-prot Accession number	O77152 (Sequence in FASTA format)
Description	Gonadotropin-releasing hormone receptor.
Source organism	Drosophila melanogaster (Fruit fly)
Taxonomical Classification	Eukaryota; Metazoa; Arthropoda; Hexapoda; Insecta; Pterygota;Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha;Ephydroidea; Drosophilidae; Drosophila.
Subcellular location	Membrane; multi-pass membrane protein (By similarity).
Developmental Stage	N/A
Similarity	N/A
Tissue Specificity	N/A
Post translational modification	N/A
Function	N/A
Protein Length	443 Amino acids
Molecular weight	50177
Domain Name	7tm_1
References	1   Hauser F., Sondergaard L., Grimmelikhuijzen C.J.P.; "Molecular cloning, genomic organization and developmental regulationof a novel receptor from Drosophila melanogaster structurally relatedto gonadotropin-releasing hormone receptors from vertebrates."; Biochem. Biophys. Res. Commun. 49:822-828(1998). 2  PubMed abstract 9731220
Hormone	N/A
Gene ID	N/A
PDB ID	N/A
Drugpedia	wiki
Comments	!Hormone for this Receptor are either unknown or have not yet been curated

Search Result - 14

HMRbase accession number	20634
Swiss-prot Accession number	Q8ITC8 (Sequence in FASTA format)
Description	Putative corazonin receptor.
Source organism	Drosophila melanogaster (Fruit fly)
Taxonomical Classification	Eukaryota; Metazoa; Arthropoda; Hexapoda; Insecta; Pterygota;Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha;Ephydroidea; Drosophilidae; Drosophila.
Subcellular location	Membrane; multi-pass membrane protein (By similarity).
Developmental Stage	N/A
Similarity	N/A
Tissue Specificity	N/A
Post translational modification	N/A
Function	N/A
Protein Length	579 Amino acids
Molecular weight	64083
Domain Name	7tm_1
References	1  PubMed abstract 12177421
Hormone	N/A
Gene ID	N/A
PDB ID	N/A
Drugpedia	wiki
Comments	!Hormone for this Receptor are either unknown or have not yet been curated

Search Result - 15

HMRbase accession number	20635
Swiss-prot Accession number	Q8MX81 (Sequence in FASTA format)
Description	Drm corazonin receptor.
Source organism	Drosophila melanogaster (Fruit fly)
Taxonomical Classification	Eukaryota; Metazoa; Arthropoda; Hexapoda; Insecta; Pterygota;Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha;Ephydroidea; Drosophilidae; Drosophila.
Subcellular location	Membrane; multi-pass membrane protein (By similarity).
Developmental Stage	N/A
Similarity	N/A
Tissue Specificity	N/A
Post translational modification	N/A
Function	N/A
Protein Length	579 Amino acids
Molecular weight	64187
Domain Name	7tm_1
References	1  PubMed abstract 12379215
Hormone	N/A
Gene ID	N/A
PDB ID	N/A
Drugpedia	wiki
Comments	!Hormone for this Receptor are either unknown or have not yet been curated

Search Result - 16

HMRbase accession number	20641
Swiss-prot Accession number	Q9VM96 (Sequence in FASTA format)
Description	CG11325-PA, isoform A (CG11325-PB, isoform B).
Source organism	Drosophila melanogaster (Fruit fly)
Taxonomical Classification	Eukaryota; Metazoa; Arthropoda; Hexapoda; Insecta; Pterygota;Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha;Ephydroidea; Drosophilidae; Drosophila.
Subcellular location	Membrane; multi-pass membrane protein (By similarity).
Developmental Stage	N/A
Similarity	N/A
Tissue Specificity	N/A
Post translational modification	N/A
Function	N/A
Protein Length	443 Amino acids
Molecular weight	50191
Domain Name	7tm_1
References	1  PubMed abstract 10731132 2  PubMed abstract 16110336 3  PubMed abstract 12537568 4  PubMed abstract 12537572 5  PubMed abstract 12537573 6   Celniker S., Carlson J., Wan K., Pfeiffer B., Frise E., George R.,Hoskins R., Stapleton M., Pacleb J., Park S., Svirskas R., Smith E.,Yu C., Rubin G.; "Drosophila melanogaster release 4 sequence."; Submitted (SEP-2006) to the EMBL/GenBank/DDBJ databases. 7   Smith C.D., Shu S., Yandell M.D., Karpen G.H.; Submitted (AUG-2006) to the EMBL/GenBank/DDBJ databases. 8   Celniker S., Carlson J., Wan K., Frise E., Hoskins R., Park S.,Svirskas R., Rubin G.; Submitted (AUG-2006) to the EMBL/GenBank/DDBJ databases. 9   Celniker S., Carlson J., Kennedy C., Wan K., Frise E., Hoskins R.,Park S., Svirskas R., Karpen G.; Submitted (AUG-2006) to the EMBL/GenBank/DDBJ databases. 10   Submitted (AUG-2006) to the EMBL/GenBank/DDBJ databases.
Hormone	N/A
Gene ID	33942
PDB ID	N/A
Drugpedia	wiki
Comments	!Hormone for this Receptor are either unknown or have not yet been curated

Search Result - 17

HMRbase accession number	20642
Swiss-prot Accession number	Q9VTW7 (Sequence in FASTA format)
Description	CG10698-PA (RE49422p).
Source organism	Drosophila melanogaster (Fruit fly)
Taxonomical Classification	Eukaryota; Metazoa; Arthropoda; Hexapoda; Insecta; Pterygota;Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha;Ephydroidea; Drosophilidae; Drosophila.
Subcellular location	Membrane; multi-pass membrane protein (By similarity).
Developmental Stage	N/A
Similarity	N/A
Tissue Specificity	N/A
Post translational modification	N/A
Function	N/A
Protein Length	579 Amino acids
Molecular weight	64115
Domain Name	7tm_1
References	1  PubMed abstract 10731132 2  PubMed abstract 16110336 3  PubMed abstract 12537568 4  PubMed abstract 12537572 5  PubMed abstract 12537573 6   Celniker S., Carlson J., Wan K., Pfeiffer B., Frise E., George R.,Hoskins R., Stapleton M., Pacleb J., Park S., Svirskas R., Smith E.,Yu C., Rubin G.; "Drosophila melanogaster release 4 sequence."; Submitted (SEP-2006) to the EMBL/GenBank/DDBJ databases. 7   Smith C.D., Shu S., Yandell M.D., Karpen G.H.; Submitted (AUG-2006) to the EMBL/GenBank/DDBJ databases. 8   Celniker S., Carlson J., Wan K., Frise E., Hoskins R., Park S.,Svirskas R., Rubin G.; Submitted (AUG-2006) to the EMBL/GenBank/DDBJ databases. 9   Celniker S., Carlson J., Kennedy C., Wan K., Frise E., Hoskins R.,Park S., Svirskas R., Karpen G.; Submitted (AUG-2006) to the EMBL/GenBank/DDBJ databases. 10   Submitted (AUG-2006) to the EMBL/GenBank/DDBJ databases. 11   Stapleton M., Brokstein P., Hong L., Agbayani A., Carlson J.,Champe M., Chavez C., Dorsett V., Dresnek D., Farfan D., Frise E.,George R., Gonzalez M., Guarin H., Kronmiller B., Li P., Liao G.,Miranda A., Mungall C.J., Nunoo J., Pacleb J., Paragas V., Park S.,Patel S., Phouanenavong S., Wan K., Yu C., Lewis S.E., Rubin G.M.,Celniker S.; Submitted (DEC-2001) to the EMBL/GenBank/DDBJ databases.
Hormone	N/A
Gene ID	39409
PDB ID	N/A
Drugpedia	wiki
Comments	!Hormone for this Receptor are either unknown or have not yet been curated

Search Result - 18

HMRbase accession number	20652
Swiss-prot Accession number	Q86C62 (Sequence in FASTA format)
Description	Putative ETH receptor splicing variant b (CG5911-PB, isoform B).
Source organism	Drosophila melanogaster (Fruit fly)
Taxonomical Classification	Eukaryota; Metazoa; Arthropoda; Hexapoda; Insecta; Pterygota;Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha;Ephydroidea; Drosophilidae; Drosophila.
Subcellular location	Membrane (By similarity)
Developmental Stage	N/A
Similarity	Belongs to the G-protein coupled receptor 1 family.
Tissue Specificity	N/A
Post translational modification	N/A
Function	N/A
Protein Length	461 Amino acids
Molecular weight	50672
Domain Name	7tm_1
References	1  PubMed abstract 12586820 2  PubMed abstract 10731132 3  PubMed abstract 16110336 4  PubMed abstract 12537568 5  PubMed abstract 12537572 6  PubMed abstract 12537573 7  PubMed abstract 12537574 8   Celniker S., Carlson J., Wan K., Pfeiffer B., Frise E., George R.,Hoskins R., Stapleton M., Pacleb J., Park S., Svirskas R., Smith E.,Yu C., Rubin G.; "Drosophila melanogaster release 4 sequence."; Submitted (AUG-2006) to the EMBL/GenBank/DDBJ databases. 9   Celniker S., Carlson J., Wan K., Frise E., Hoskins R., Park S.,Svirskas R., Rubin G.; Submitted (AUG-2006) to the EMBL/GenBank/DDBJ databases. 10   FlyBase; Submitted (AUG-2006) to the EMBL/GenBank/DDBJ databases. 11   Celniker S., Carlson J., Kennedy C., Wan K., Frise E., Hoskins R.,Park S., Svirskas R., Karpen G.; Submitted (AUG-2006) to the EMBL/GenBank/DDBJ databases.
Hormone	N/A
Gene ID	42523
PDB ID	N/A
Drugpedia	wiki
Comments	!Hormone for this Receptor are either unknown or have not yet been curated

Search Result - 19

HMRbase accession number	20656
Swiss-prot Accession number	Q9VDC4 (Sequence in FASTA format)
Description	CG5911-PA, isoform A (Putative ETH receptor splicing variant a).
Source organism	Drosophila melanogaster (Fruit fly)
Taxonomical Classification	Eukaryota; Metazoa; Arthropoda; Hexapoda; Insecta; Pterygota;Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha;Ephydroidea; Drosophilidae; Drosophila.
Subcellular location	Membrane (By similarity)
Developmental Stage	N/A
Similarity	Belongs to the G-protein coupled receptor 1 family.
Tissue Specificity	N/A
Post translational modification	N/A
Function	N/A
Protein Length	471 Amino acids
Molecular weight	52774
Domain Name	7tm_1
References	1  PubMed abstract 10731132 2  PubMed abstract 16110336 3  PubMed abstract 12537568 4  PubMed abstract 12537572 5  PubMed abstract 12537573 6  PubMed abstract 12537574 7   Celniker S., Carlson J., Wan K., Pfeiffer B., Frise E., George R.,Hoskins R., Stapleton M., Pacleb J., Park S., Svirskas R., Smith E.,Yu C., Rubin G.; "Drosophila melanogaster release 4 sequence."; Submitted (AUG-2006) to the EMBL/GenBank/DDBJ databases. 8   Celniker S., Carlson J., Wan K., Frise E., Hoskins R., Park S.,Svirskas R., Rubin G.; Submitted (AUG-2006) to the EMBL/GenBank/DDBJ databases. 9   FlyBase; Submitted (AUG-2006) to the EMBL/GenBank/DDBJ databases. 10   Celniker S., Carlson J., Kennedy C., Wan K., Frise E., Hoskins R.,Park S., Svirskas R., Karpen G.; Submitted (AUG-2006) to the EMBL/GenBank/DDBJ databases. 11  PubMed abstract 12586820
Hormone	N/A
Gene ID	42523
PDB ID	N/A
Drugpedia	wiki
Comments	!Hormone for this Receptor are either unknown or have not yet been curated

Search Result - 20

HMRbase accession number	21124
Swiss-prot Accession number	Q71EB3 (Sequence in FASTA format)
Description	Putative AKH receptor.
Source organism	Drosophila melanogaster (Fruit fly)
Taxonomical Classification	Eukaryota; Metazoa; Arthropoda; Hexapoda; Insecta; Pterygota;Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha;Ephydroidea; Drosophilidae; Drosophila.
Subcellular location	Membrane; multi-pass membrane protein (By similarity).
Developmental Stage	N/A
Similarity	N/A
Tissue Specificity	N/A
Post translational modification	N/A
Function	N/A
Protein Length	455 Amino acids
Molecular weight	51437
Domain Name	7tm_1
References	1  PubMed abstract 12177421
Hormone	P61855   Detail in HMRbase
Gene ID	N/A
PDB ID	N/A
Drugpedia	wiki
Comments

Search Result - 21

HMRbase accession number	21205
Swiss-prot Accession number	P16375 (Sequence in FASTA format)
Description	RecName: Steroid receptor seven-up, isoforms B/C;Alternative Name: Nuclear receptor subfamily 2 group F member 3, isoforms B/C;
Source organism	Drosophila melanogaster (Fruit fly)
Taxonomical Classification	Eukaryota; Metazoa; Arthropoda; Hexapoda; Insecta; Pterygota;Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha;Ephydroidea; Drosophilidae; Drosophila; Sophophora.
Subcellular location	Nucleus (Potential)
Developmental Stage	N/A
Similarity	Belongs to the nuclear hormone receptor family. NR2 subfamily. Contains 1 nuclear receptor DNA-binding domain.
Tissue Specificity	Expressed in several embryonic tissues; dorsal vessel, oenocyte and fat body. CNS expression is dynamic and confined to temporally restricted subsections of the NB lineage; expressed in many NB and GMCs, but only a small number of neurons.
Post translational modification	N/A
Function	Receptor that is required in photoreceptors R1, R3, R4 and R6 during eye development; generation of the ganglion mother cell-2 (GMC-2) fate in the nb7-3 lineage, coinciding with the transition in the expression of HB to KR in the neuroblasts (NBs).
Protein Length	543 Amino acids
Molecular weight	57988
Domain Name	Hormone_recep  zf-C4  zf-C4_C
References	1  PubMed abstract 2105166 2  PubMed abstract 10731132 3  PubMed abstract 12537572 4  PubMed abstract 12537569 5  PubMed abstract 15691762
Hormone	N/A
Gene ID	41491
PDB ID	N/A
Drugpedia	wiki
Comments	!Hormone for this Receptor are either unknown or have not yet been curated

Search Result - 22

HMRbase accession number	21206
Swiss-prot Accession number	P16376 (Sequence in FASTA format)
Description	RecName: Steroid receptor seven-up, isoform A;Alternative Name: Nuclear receptor subfamily 2 group F member 3, isoform A;
Source organism	Drosophila melanogaster (Fruit fly)
Taxonomical Classification	Eukaryota; Metazoa; Arthropoda; Hexapoda; Insecta; Pterygota;Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha;Ephydroidea; Drosophilidae; Drosophila; Sophophora.
Subcellular location	Nucleus (Potential)
Developmental Stage	N/A
Similarity	Belongs to the nuclear hormone receptor family. NR2 subfamily. Contains 1 nuclear receptor DNA-binding domain.
Tissue Specificity	Expressed in several embryonic tissues; dorsal vessel, oenocyte and fat body. CNS expression is dynamic and confined to temporally restricted subsections of the NB lineage; expressed in many NB and GMCs, but only a small number of neurons.
Post translational modification	N/A
Function	Receptor that is required in photoreceptors R1, R3, R4 and R6 during eye development; generation of the ganglion mother cell-2 (GMC-2) fate in the nb7-3 lineage, coinciding with the transition in the expression of HB to KR in the neuroblasts (NBs).
Protein Length	746 Amino acids
Molecular weight	76814
Domain Name	Hormone_recep  zf-C4  zf-C4_C
References	1  PubMed abstract 2105166 2  PubMed abstract 10731132 3  PubMed abstract 12537572 4  PubMed abstract 15691762
Hormone	N/A
Gene ID	41491
PDB ID	N/A
Drugpedia	wiki
Comments	!Hormone for this Receptor are either unknown or have not yet been curated

Search Result - 23

HMRbase accession number	21228
Swiss-prot Accession number	P17672 (Sequence in FASTA format)
Description	RecName: Ecdysone-induced protein 75B, isoform A;E75-B;Alternative Name: Nuclear receptor subfamily 1 group D member 3, isoform A;
Source organism	Drosophila melanogaster (Fruit fly)
Taxonomical Classification	Eukaryota; Metazoa; Arthropoda; Hexapoda; Insecta; Pterygota;Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha;Ephydroidea; Drosophilidae; Drosophila; Sophophora.
Subcellular location	Nucleus (Potential)
Developmental Stage	In mid instar larvae salivary glands, levels are low during puff stage 1, increase during puff stages 2-4 and diminish from stage 5 onwards. In prepupae, isoform A is the predominant form during puff stage 19 and the transition to stage 20. By stage 3 it is present in the gut, Malpighian tubules and the fat body, levels persist beyond stage 11.
Similarity	Belongs to the nuclear hormone receptor family. NR1 subfamily. Contains 1 nuclear receptor DNA-binding domain.
Tissue Specificity	N/A
Post translational modification	N/A
Function	Implicated in the regulation of ecdysone-triggered gene hierarchies. Probably plays a key role in mediating the regulation of the larval molt by 20-OH-ecdysone.
Protein Length	1355 Amino acids
Molecular weight	147171
Domain Name	Hormone_recep  zf-C4
References	1  PubMed abstract 2110921 2  PubMed abstract 10731132 3  PubMed abstract 12537572 4  PubMed abstract 8223281
Hormone	Detail in HMRbase
Gene ID	39999
PDB ID	N/A
Drugpedia	wiki
Comments

Search Result - 24

HMRbase accession number	21229
Swiss-prot Accession number	P13055 (Sequence in FASTA format)
Description	RecName: Ecdysone-induced protein 75B, isoform B;Alternative Name: E75-C;Alternative Name: Nuclear receptor subfamily 1 group D member 3, isoform B;
Source organism	Drosophila melanogaster (Fruit fly)
Taxonomical Classification	Eukaryota; Metazoa; Arthropoda; Hexapoda; Insecta; Pterygota;Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha;Ephydroidea; Drosophilidae; Drosophila; Sophophora.
Subcellular location	Nucleus (Potential)
Developmental Stage	In mid instar larvae salivary glands, levels increase during puff stage 1, then remain relatively constant until the premetamorphic pulse of ecdysone at puff stage 5. Levels increase again in late larvae at puff stages 9-10. At puff stage 1 expression is also seen in the gut. Levels are low in the gut, Malpighian tubules, fat body and wing disks between stages 1 and 11.
Similarity	Belongs to the nuclear hormone receptor family. NR1 subfamily. Contains 1 nuclear receptor DNA-binding domain.
Tissue Specificity	N/A
Post translational modification	N/A
Function	Implicated in the regulation of ecdysone-triggered gene hierarchies. Probably plays a key role in mediating the regulation of the larval molt by 20-OH-ecdysone.
Protein Length	1412 Amino acids
Molecular weight	151292
Domain Name	Hormone_recep  zf-C4
References	1  PubMed abstract 2508058 2  PubMed abstract 10731132 3  PubMed abstract 12537572 4  PubMed abstract 8223281
Hormone	Detail in HMRbase
Gene ID	39999
PDB ID	N/A
Drugpedia	wiki
Comments

Search Result - 25

HMRbase accession number	21230
Swiss-prot Accession number	P17671 (Sequence in FASTA format)
Description	RecName: Ecdysone-induced protein 75B, isoforms C/D;Alternative Name: E75-A;Alternative Name: Nuclear receptor subfamily 1 group D member 3, isoforms C/D;
Source organism	Drosophila melanogaster (Fruit fly)
Taxonomical Classification	Eukaryota; Metazoa; Arthropoda; Hexapoda; Insecta; Pterygota;Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha;Ephydroidea; Drosophilidae; Drosophila; Sophophora.
Subcellular location	Nucleus (Potential)
Developmental Stage	In mid instar larvae salivary glands, low basal levels are observed in puff stage 1. Levels increase in late larvae from puff stages 3-10, then decrease abruptly at stage 11. In prepupae, isoform C is the predominant form during the transition between puff stages 18-19. At puff stage 1, expression is also present in the gut. By stage 3 it is present in the wing disks, Malpighian tubules and the fat body. At stage 11, expression is only present in the gut and wing disks.
Similarity	Belongs to the nuclear hormone receptor family. NR1 subfamily. Contains 1 nuclear receptor DNA-binding domain.
Tissue Specificity	N/A
Post translational modification	N/A
Function	Implicated in the regulation of ecdysone-triggered gene hierarchies. Probably plays a key role in mediating the regulation of the larval molt by 20-OH-ecdysone.
Protein Length	1199 Amino acids
Molecular weight	128534
Domain Name	Hormone_recep  zf-C4
References	1  PubMed abstract 2110921 2  PubMed abstract 10731132 3  PubMed abstract 12537572 4  PubMed abstract 8223281
Hormone	Detail in HMRbase
Gene ID	39999
PDB ID	N/A
Drugpedia	wiki
Comments

Search Result - 26

HMRbase accession number	21234
Swiss-prot Accession number	P45447 (Sequence in FASTA format)
Description	RecName: Ecdysone-induced protein 78C;DR-78;Alternative Name: Nuclear receptor subfamily 1 group E member 1;
Source organism	Drosophila melanogaster (Fruit fly)
Taxonomical Classification	Eukaryota; Metazoa; Arthropoda; Hexapoda; Insecta; Pterygota;Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha;Ephydroidea; Drosophilidae; Drosophila; Sophophora.
Subcellular location	Nucleus (Probable)
Developmental Stage	Isoform A is expressed only in mid-pupal stages, while isoform B is maximally expressed in newly formed prepupae and immediately following isoform A in mid-pupae.
Similarity	Belongs to the nuclear hormone receptor family. NR1 subfamily. Contains 1 nuclear receptor DNA-binding domain.
Tissue Specificity	N/A
Post translational modification	N/A
Function	Induces the early late puff 78C which triggers puparium formation and development.
Protein Length	866 Amino acids
Molecular weight	95250
Domain Name	Hormone_recep  zf-C4
References	1  PubMed abstract 8402914 2  PubMed abstract 8878682 3  PubMed abstract 10731132 4  PubMed abstract 12537572 5  PubMed abstract 8241283
Hormone	Detail in HMRbase
Gene ID	40345
PDB ID	N/A
Drugpedia	wiki
Comments

Search Result - 27

HMRbase accession number	21238
Swiss-prot Accession number	P34021 (Sequence in FASTA format)
Description	RecName: Ecdysone receptor;Alternative Name: Ecdysteroid receptor;Alternative Name: 20-hydroxy-ecdysone receptor;20E receptor;Alternative Name: EcRH;Alternative Name: Nuclear receptor subfamily 1 group H member 1;
Source organism	Drosophila melanogaster (Fruit fly)
Taxonomical Classification	Eukaryota; Metazoa; Arthropoda; Hexapoda; Insecta; Pterygota;Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha;Ephydroidea; Drosophilidae; Drosophila; Sophophora.
Subcellular location	Nucleus
Developmental Stage	In the salivary glands of mid instar larvae levels increase during puff stage 1 at 86-94 hours of development then remain relatively constant until the premetamorphic pulse of ecdysone in late larvae. Levels diminish dramatically from puff stage 7 onwards. Levels increase in the prepupal period during puff stage 13-14, the level remains stable until stage 21. A decrease in levels at puff stage 7 is also seen in the Malpighian tubules and less dramatically in the fat body and gut. In the wing disk the relatively low level remains unchanged.
Similarity	Belongs to the nuclear hormone receptor family. NR1 subfamily. Contains 1 nuclear receptor DNA-binding domain.
Tissue Specificity	Isoform B1 predominates over isoform A in larval tissues, imaginal histoblast nests and midgut islands. Isoform A predominates over B1 in imaginal disks, and the larval prothoracic gland.
Post translational modification	N/A
Function	Receptor for ecdysone. Binds to ecdysone response elements (ECRES) following ecdysone-binding, and recruitment of a complex containing the histone methyltransferase trr, leads to activate transcription of target genes.
Protein Length	878 Amino acids
Molecular weight	93853
Domain Name	Hormone_recep  zf-C4
References	1  PubMed abstract 1913820 2  PubMed abstract 10731132 3  PubMed abstract 12537572 4  PubMed abstract 12537569 5  PubMed abstract 8324824 6  PubMed abstract 8247157 7  PubMed abstract 8223281 8  PubMed abstract 14603321
Hormone	Detail in HMRbase
Gene ID	35540
PDB ID	1R0N   1R0O   2HAN
Drugpedia	wiki
Comments

Search Result - 28

HMRbase accession number	21242
Swiss-prot Accession number	P15370 (Sequence in FASTA format)
Description	RecName: Protein embryonic gonad;Alternative Name: Protein eagle;Alternative Name: Protein spready;Alternative Name: Nuclear receptor subfamily 0 group A member 3;
Source organism	Drosophila melanogaster (Fruit fly)
Taxonomical Classification	Eukaryota; Metazoa; Arthropoda; Hexapoda; Insecta; Pterygota;Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha;Ephydroidea; Drosophilidae; Drosophila; Sophophora.
Subcellular location	Nucleus (Potential)
Developmental Stage	N/A
Similarity	Belongs to the nuclear hormone receptor family. NR0 subfamily. Contains 1 nuclear receptor DNA-binding domain.
Tissue Specificity	During embryonic stages 10 and 11, expression was observed in four neuroblasts, NB2-4, NB3-3, NB6-4 and NB7-3. Except for NB6-4, expression reaches a maximum at the very beginning of expression or in the period of neuroblast delamination. Weak expression is also observed in a few putative progeny of NB7-3 during late embryonic stage 11 and 12. All eagle expression in abdominal segments disappears by stage 13.
Post translational modification	N/A
Function	May play a critical role in development of the progeny of eagle-positive neuroblasts.
Protein Length	373 Amino acids
Molecular weight	39561
Domain Name	zf-C4
References	1  PubMed abstract 2555153 2  PubMed abstract 8625804 3  PubMed abstract 10731132 4  PubMed abstract 12537572
Hormone	N/A
Gene ID	40428
PDB ID	N/A
Drugpedia	wiki
Comments	!Hormone for this Receptor are either unknown or have not yet been curated

Search Result - 29

HMRbase accession number	21320
Swiss-prot Accession number	P49866 (Sequence in FASTA format)
Description	RecName: Transcription factor HNF-4 homolog;Alternative Name: dHNF4;Alternative Name: Nuclear receptor subfamily 2 group A member 4;
Source organism	Drosophila melanogaster (Fruit fly)
Taxonomical Classification	Eukaryota; Metazoa; Arthropoda; Hexapoda; Insecta; Pterygota;Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha;Ephydroidea; Drosophilidae; Drosophila; Sophophora.
Subcellular location	Nucleus
Developmental Stage	N/A
Similarity	Belongs to the nuclear hormone receptor family. NR2 subfamily. Contains 1 nuclear receptor DNA-binding domain.
Tissue Specificity	In developing embryos it is expressed in mid- gut, fat bodies and the distal region of Malpighian tubules.
Post translational modification	N/A
Function	Transcriptionally controlled transcription factor. Important for the differentiation of various specialized cell types that arise from both endoderm and mesoderm. May have a role in early gut formation.
Protein Length	666 Amino acids
Molecular weight	71900
Domain Name	Hormone_recep  zf-C4
References	1  PubMed abstract 8440243 2  PubMed abstract 10731132 3  PubMed abstract 12537572
Hormone	N/A
Gene ID	44544
PDB ID	N/A
Drugpedia	wiki
Comments	!Hormone for this Receptor are either unknown or have not yet been curated

Search Result - 30

HMRbase accession number	21321
Swiss-prot Accession number	P10734 (Sequence in FASTA format)
Description	RecName: Zygotic gap protein knirps;Alternative Name: Nuclear receptor subfamily 0 group A member 1;
Source organism	Drosophila melanogaster (Fruit fly)
Taxonomical Classification	Eukaryota; Metazoa; Arthropoda; Hexapoda; Insecta; Pterygota;Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha;Ephydroidea; Drosophilidae; Drosophila; Sophophora.
Subcellular location	Nucleus
Developmental Stage	N/A
Similarity	Belongs to the nuclear hormone receptor family. NR0 subfamily. Contains 1 nuclear receptor DNA-binding domain.
Tissue Specificity	N/A
Post translational modification	N/A
Function	Transcriptional repressor. Binds to multiple sites in the eve stripe 3 enhancer element. Plays an essential role in the segmentation process both by refining the expression patterns of gap genes and by establishing pair-rules stripes of gene expression.
Protein Length	429 Amino acids
Molecular weight	45611
Domain Name	zf-C4
References	1  PubMed abstract 2904128 2  PubMed abstract 10731132 3  PubMed abstract 12537572 4  PubMed abstract 12537569 5  PubMed abstract 8670869
Hormone	N/A
Gene ID	40287
PDB ID	N/A
Drugpedia	wiki
Comments	!Hormone for this Receptor are either unknown or have not yet been curated

Search Result - 31

HMRbase accession number	21323
Swiss-prot Accession number	P13054 (Sequence in FASTA format)
Description	RecName: Knirps-related protein;Alternative Name: Nuclear receptor subfamily 0 group A member 2;
Source organism	Drosophila melanogaster (Fruit fly)
Taxonomical Classification	Eukaryota; Metazoa; Arthropoda; Hexapoda; Insecta; Pterygota;Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha;Ephydroidea; Drosophilidae; Drosophila; Sophophora.
Subcellular location	Nucleus
Developmental Stage	N/A
Similarity	Belongs to the nuclear hormone receptor family. NR0 subfamily. Contains 1 nuclear receptor DNA-binding domain.
Tissue Specificity	N/A
Post translational modification	N/A
Function	N/A
Protein Length	647 Amino acids
Molecular weight	68322
Domain Name	zf-C4
References	1  PubMed abstract 2848202 2  PubMed abstract 10731132 3  PubMed abstract 12537572 4  PubMed abstract 12537569
Hormone	N/A
Gene ID	40285
PDB ID	N/A
Drugpedia	wiki
Comments	!Hormone for this Receptor are either unknown or have not yet been curated

Search Result - 32

HMRbase accession number	21496
Swiss-prot Accession number	P18102 (Sequence in FASTA format)
Description	Protein tailless;Alternative Name: Nuclear receptor subfamily 2 group E member 2
Source organism	Drosophila melanogaster (Fruit fly)
Taxonomical Classification	Eukaryota; Metazoa; Arthropoda; Hexapoda; Insecta; Pterygota;Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha;Ephydroidea; Drosophilidae; Drosophila; Sophophora.
Subcellular location	Nucleus (Potential)
Developmental Stage	During stage 10 found in the anterior part of the visual system that later gives rise to the anterior lip of the optic lobe. At stage 12 also found in the posterior lip of the optic lobe. In third larval instar expressed in the optic lobe of the larval brain and in the eye antennal disk, both in antennal and eye portion.
Similarity	Belongs to the nuclear hormone receptor family. NR2 subfamily. Contains 1 nuclear receptor DNA-binding domain.
Tissue Specificity	Brain and peripheral nervous system.
Post translational modification	N/A
Function	Orphan receptor that binds DNA as a monomer to hormone response elements (HRE) containing an extended core motif half- site sequence 5'-AAGTCA-3' in which the 5' flanking nucleotides participate in determining receptor specificity. This receptor binds to the consensus sequence [AG][AG]AAGTCAA. Plays a key role in the establishment of non-metameric domains at the anterior and posterior poles of the embryo. It may also play a role in the nervous system. The maternal terminal pathway activates the tll gene in the termini; TLL activity then represses segmentation and activates terminal-specific genes in these domains. Involved in the regulation of early eye development. In the embryonic visual system anlage drives cells to optic lobe as opposed to Bolwig's organ fate.
Protein Length	452 Amino acids
Molecular weight	50549
Domain Name	Hormone_recep  zf-C4
References	1  PubMed abstract 2364433 2  PubMed abstract 8430097 3  PubMed abstract 10731132 4  PubMed abstract 12537572 5  PubMed abstract 10357938
Hormone	N/A
Gene ID	43656
PDB ID	N/A
Drugpedia	wiki
Comments	!Hormone for this Receptor are either unknown or have not yet been curated

Search Result - 33

HMRbase accession number	21499
Swiss-prot Accession number	P20153 (Sequence in FASTA format)
Description	Protein ultraspiracle;Alternative Name: XR2C;Alternative Name: Chorion factor 1;Alternative Name: Nuclear receptor subfamily 2 group B member 4
Source organism	Drosophila melanogaster (Fruit fly)
Taxonomical Classification	Eukaryota; Metazoa; Arthropoda; Hexapoda; Insecta; Pterygota;Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha;Ephydroidea; Drosophilidae; Drosophila; Sophophora.
Subcellular location	Nucleus
Developmental Stage	N/A
Similarity	Belongs to the nuclear hormone receptor family. NR2 subfamily. Contains 1 nuclear receptor DNA-binding domain.
Tissue Specificity	N/A
Post translational modification	N/A
Function	Receptor for ecdysone. May be an important modulator of insect metamorphosis. Plays an important part in embryonic and post-embryonic development. Binds to ecdysone response elements (ECRES) such as in the promoter region of s15 chorion gene.
Protein Length	508 Amino acids
Molecular weight	55244
Domain Name	Hormone_recep  zf-C4
References	1  PubMed abstract 2169594 2  PubMed abstract 2165589 3  PubMed abstract 10731132 4  PubMed abstract 12537572 5  PubMed abstract 10731137 6  PubMed abstract 12537569 7  PubMed abstract 2120114 8  PubMed abstract 8247157 9  PubMed abstract 18327897
Hormone	N/A
Gene ID	31165
PDB ID	1HG4   1R0O   2HAN
Drugpedia	wiki
Comments	!Hormone for this Receptor are either unknown or have not yet been curated

Search Result - 34

HMRbase accession number	21907
Swiss-prot Accession number	O96680 (Sequence in FASTA format)
Description	Dissatisfaction
Source organism	Drosophila melanogaster (Fruit fly)
Taxonomical Classification	Eukaryota; Metazoa; Arthropoda; Hexapoda; Insecta; Pterygota;Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha;Ephydroidea; Drosophilidae; Drosophila; Sophophora.
Subcellular location	N/A
Developmental Stage	N/A
Similarity	Belongs to the nuclear hormone receptor family. Contains 1 nuclear receptor DNA-binding domain.
Tissue Specificity	N/A
Post translational modification	N/A
Function	N/A
Protein Length	693 Amino acids
Molecular weight	74265
Domain Name	Hormone_recep  zf-C4
References	1  PubMed abstract 9883729
Hormone	N/A
Gene ID	N/A
PDB ID	N/A
Drugpedia	wiki
Comments	!Hormone for this Receptor are either unknown or have not yet been curated

Search Result - 35

HMRbase accession number	22436
Swiss-prot Accession number	Q8IGG2 (Sequence in FASTA format)
Description	RH29074p; Fragment
Source organism	Drosophila melanogaster (Fruit fly)
Taxonomical Classification	Eukaryota; Metazoa; Arthropoda; Hexapoda; Insecta; Pterygota;Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha;Ephydroidea; Drosophilidae; Drosophila; Sophophora.
Subcellular location	Nucleus
Developmental Stage	N/A
Similarity	Belongs to the nuclear hormone receptor family. Contains 1 nuclear receptor DNA-binding domain.
Tissue Specificity	N/A
Post translational modification	N/A
Function	N/A
Protein Length	738 Amino acids
Molecular weight	79661
Domain Name	Hormone_recep  zf-C4
References	----
Hormone	N/A
Gene ID	N/A
PDB ID	N/A
Drugpedia	wiki
Comments	!Hormone for this Receptor are either unknown or have not yet been curated

Search Result - 36

HMRbase accession number	22437
Swiss-prot Accession number	Q8INU7 (Sequence in FASTA format)
Description	CG1864-PC, isoform C
Source organism	Drosophila melanogaster (Fruit fly)
Taxonomical Classification	Eukaryota; Metazoa; Arthropoda; Hexapoda; Insecta; Pterygota;Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha;Ephydroidea; Drosophilidae; Drosophila; Sophophora.
Subcellular location	N/A
Developmental Stage	N/A
Similarity	Belongs to the nuclear hormone receptor family. Contains 1 nuclear receptor DNA-binding domain.
Tissue Specificity	N/A
Post translational modification	N/A
Function	N/A
Protein Length	556 Amino acids
Molecular weight	61254
Domain Name	Hormone_recep  zf-C4
References	1  PubMed abstract 12537572 2  PubMed abstract 10731132
Hormone	N/A
Gene ID	35332
PDB ID	N/A
Drugpedia	wiki
Comments	!Hormone for this Receptor are either unknown or have not yet been curated

Search Result - 37

HMRbase accession number	22438
Swiss-prot Accession number	Q8IPF2 (Sequence in FASTA format)
Description	CG9310-PB, isoform B
Source organism	Drosophila melanogaster (Fruit fly)
Taxonomical Classification	Eukaryota; Metazoa; Arthropoda; Hexapoda; Insecta; Pterygota;Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha;Ephydroidea; Drosophilidae; Drosophila; Sophophora.
Subcellular location	Nucleus
Developmental Stage	N/A
Similarity	Belongs to the nuclear hormone receptor family. Contains 1 nuclear receptor DNA-binding domain.
Tissue Specificity	N/A
Post translational modification	N/A
Function	N/A
Protein Length	732 Amino acids
Molecular weight	78959
Domain Name	Hormone_recep  zf-C4
References	1  PubMed abstract 12537572 2  PubMed abstract 10731132
Hormone	N/A
Gene ID	44544
PDB ID	N/A
Drugpedia	wiki
Comments	!Hormone for this Receptor are either unknown or have not yet been curated

Search Result - 38

HMRbase accession number	22515
Swiss-prot Accession number	Q8SXA4 (Sequence in FASTA format)
Description	GH21112p (CG33183-PB, isoform B)
Source organism	Drosophila melanogaster (Fruit fly)
Taxonomical Classification	Eukaryota; Metazoa; Arthropoda; Hexapoda; Insecta; Pterygota;Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha;Ephydroidea; Drosophilidae; Drosophila; Sophophora.
Subcellular location	N/A
Developmental Stage	N/A
Similarity	Belongs to the nuclear hormone receptor family. Contains 1 nuclear receptor DNA-binding domain.
Tissue Specificity	N/A
Post translational modification	N/A
Function	N/A
Protein Length	444 Amino acids
Molecular weight	50581
Domain Name	Hormone_recep  zf-C4
References	1  PubMed abstract 12537572 2  PubMed abstract 10731132
Hormone	N/A
Gene ID	36073
PDB ID	N/A
Drugpedia	wiki
Comments	!Hormone for this Receptor are either unknown or have not yet been curated

Search Result - 39

HMRbase accession number	22544
Swiss-prot Accession number	Q8WS79 (Sequence in FASTA format)
Description	Estrogen-related receptor splice variant (CG7404-PB, isoform B)
Source organism	Drosophila melanogaster (Fruit fly)
Taxonomical Classification	Eukaryota; Metazoa; Arthropoda; Hexapoda; Insecta; Pterygota;Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha;Ephydroidea; Drosophilidae; Drosophila; Sophophora.
Subcellular location	N/A
Developmental Stage	N/A
Similarity	Belongs to the nuclear hormone receptor family. Contains 1 nuclear receptor DNA-binding domain.
Tissue Specificity	N/A
Post translational modification	N/A
Function	N/A
Protein Length	496 Amino acids
Molecular weight	54530
Domain Name	Hormone_recep  zf-C4
References	1  PubMed abstract 18327897 2  PubMed abstract 12537572 3  PubMed abstract 10731132
Hormone	N/A
Gene ID	38912
PDB ID	N/A
Drugpedia	wiki
Comments	!Hormone for this Receptor are either unknown or have not yet been curated

Search Result - 40

HMRbase accession number	22907
Swiss-prot Accession number	Q9VI12 (Sequence in FASTA format)
Description	CG10296-PA
Source organism	Drosophila melanogaster (Fruit fly)
Taxonomical Classification	Eukaryota; Metazoa; Arthropoda; Hexapoda; Insecta; Pterygota;Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha;Ephydroidea; Drosophilidae; Drosophila; Sophophora.
Subcellular location	N/A
Developmental Stage	N/A
Similarity	Belongs to the nuclear hormone receptor family. Contains 1 nuclear receptor DNA-binding domain.
Tissue Specificity	N/A
Post translational modification	N/A
Function	N/A
Protein Length	278 Amino acids
Molecular weight	31062
Domain Name	zf-C4
References	1  PubMed abstract 12537572 2  PubMed abstract 10731132
Hormone	N/A
Gene ID	40783
PDB ID	N/A
Drugpedia	wiki
Comments	!Hormone for this Receptor are either unknown or have not yet been curated

Search Result - 41

HMRbase accession number	22908
Swiss-prot Accession number	Q9VLI7 (Sequence in FASTA format)
Description	CG9310-PA, isoform A;RE09535p
Source organism	Drosophila melanogaster (Fruit fly)
Taxonomical Classification	Eukaryota; Metazoa; Arthropoda; Hexapoda; Insecta; Pterygota;Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha;Ephydroidea; Drosophilidae; Drosophila; Sophophora.
Subcellular location	Nucleus
Developmental Stage	N/A
Similarity	Belongs to the nuclear hormone receptor family. Contains 1 nuclear receptor DNA-binding domain.
Tissue Specificity	N/A
Post translational modification	N/A
Function	N/A
Protein Length	704 Amino acids
Molecular weight	76388
Domain Name	Hormone_recep  zf-C4
References	1  PubMed abstract 12537572 2  PubMed abstract 10731132
Hormone	N/A
Gene ID	44544
PDB ID	N/A
Drugpedia	wiki
Comments	!Hormone for this Receptor are either unknown or have not yet been curated

Search Result - 42

HMRbase accession number	22909
Swiss-prot Accession number	Q9VML1 (Sequence in FASTA format)
Description	CG9019-PA
Source organism	Drosophila melanogaster (Fruit fly)
Taxonomical Classification	Eukaryota; Metazoa; Arthropoda; Hexapoda; Insecta; Pterygota;Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha;Ephydroidea; Drosophilidae; Drosophila; Sophophora.
Subcellular location	N/A
Developmental Stage	N/A
Similarity	Belongs to the nuclear hormone receptor family. Contains 1 nuclear receptor DNA-binding domain.
Tissue Specificity	N/A
Post translational modification	N/A
Function	N/A
Protein Length	691 Amino acids
Molecular weight	74053
Domain Name	Hormone_recep  zf-C4
References	1  PubMed abstract 10731132 2  PubMed abstract 12537572
Hormone	N/A
Gene ID	33823
PDB ID	N/A
Drugpedia	wiki
Comments	!Hormone for this Receptor are either unknown or have not yet been curated

Search Result - 43

HMRbase accession number	22910
Swiss-prot Accession number	Q9VSE9 (Sequence in FASTA format)
Description	CG7404-PA, isoform A;Estrogen-related receptor;GH28308p
Source organism	Drosophila melanogaster (Fruit fly)
Taxonomical Classification	Eukaryota; Metazoa; Arthropoda; Hexapoda; Insecta; Pterygota;Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha;Ephydroidea; Drosophilidae; Drosophila; Sophophora.
Subcellular location	N/A
Developmental Stage	N/A
Similarity	Belongs to the nuclear hormone receptor family. Contains 1 nuclear receptor DNA-binding domain.
Tissue Specificity	N/A
Post translational modification	N/A
Function	N/A
Protein Length	484 Amino acids
Molecular weight	53245
Domain Name	Hormone_recep  zf-C4
References	1  PubMed abstract 10731132 2  PubMed abstract 12537572
Hormone	N/A
Gene ID	38912
PDB ID	N/A
Drugpedia	wiki
Comments	!Hormone for this Receptor are either unknown or have not yet been curated